After logging 100k plus in a truck with a rear Detroit I'm not inclined to use anything else. In fact I'm looking for one for my 92, but the 32 spline versions are pricey.
Downsides of a detroit:noise, especially clanks and clunks as the extra lash in the driveline takes up. Kind of sounds like sloppy u joints. Occasional pull one way or the other but this is usually caused by mismatched tires or uneven pressures.
upsides: no brainer operation, minimal maitainence (change oil once in a while) no additives needed either, will always give power to tire with best traction.
There's a reason it's been on the market forever and for just about every axle ever built.