If the B20 is to spec, you should not notice or have to do anything.
If you have crap in your tank, the B20 will clean it out and plug your filter.
Do you know what their feed stock is? WVO, Soy and Algae are the three bigger players nowadays.
I like B20 for the higher Cetane rating and the WVO stuff gives a hint of McDonald's to the people behind you.
If you go any higher than B50, you will need to change oil more often and worry about gelling in cold weather.