I ran 2" leveling kit on my old 95 Ram 1500, they are basically the same setup up front as the 2500 just heavier coil springs. My 2" Rough County leveling worked great and cleared that size tire with no problems at all, even on aftermarket rims. Mine always aligned fine with no out of spec specs. From my understanding 2" leveling is the most you can go before you run into problems.
2000 Dodge Ram 2500 4x4 White Extended Cab, Garmonized 47RE Triple Disc TC, Smarty/ADR w/iQuad, 5" straight pipe to 6" tip, AFE stage 2 CAI, Amsoil Dual oil filtering kit, Boost Elbow, Raptor 150 fuel pump,On-board Air and Train Horn, 2" Leveling kit