Thanks to all. I think I have things back going again, but not to confident. Think I must have picked up some bad fuel somewhere along the trip. I wired right off the battery and crawled under the truck. I could hear the pumps motors trying to run but nothing happening. Changed the fuel filter and gently tapped on the Pumps with the biggest pipe wrench I have and whatever the problem was they broke lose. When I hooked the trigger wire back up to the ECM were back to working fine now, again, for now.
I'm still looking for opinions on what happened here though, in case it is still a problem in the future.
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99 Quad Cab, 4wd, Comp Box W/Pump Wire & Boost Elbow installed, K&N Air Canon, MBRP exhaust, Twin PE 4200 High Pressure Fuel Pumps W/Fleetguard inline filter, Isspro EV Pyrometer, Boost Guage, Fuel Pressure Guage, DT Pro Fab Trac Bar, South Bend 13-1.25 Con O Clutch, Royal Purple Synthetics all around
374.2/846.7 at 30psi